Published Papers

2024

  • Early human fetal lung atlas reveals the temporal dynamics of epithelial cell plasticity (Nature comm.)
  • Fatecode enables cell fate regulator prediction using classification-supervised autoencoder perturbation (Cell Reports Methods)

2023

  • Inferring single-cell transcriptomic dynamics with structured latent gene expression dynamics (Cell Reports)
  • petiteFinder: an automated computer vision tool to compute Petite colony frequencies in baker’s yeast (BMC Bioinformatics)

2022

  • N Leibovich, J Rothschild, S Goyal, A Zilman – “Phenomenology and dynamics of competitive ecosystems beyond the niche-neutral regimes” (PNAS, arxiv)
  • CJ Nunn, S Goyal – “Contingency and selection in mitochondrial genome dynamics” (eLife)
  • C Nunn, S Goyal – “Population dynamics of mitochondrial genomes in Saccharomyces cerevisiae reveal tightly constrained mutational trajectories and a simple relationship between genome content and replicative fitness” (APS)
  • S Goyal, S Rehman, C O’Brien – “Statistical dynamics of tumor initiation and progression” (APS)
  • M Bonsma-Fisher, S Goyal – “Diversity-generating host-disease coevolution with adaptive immunity” (APS)
  • S Freedman, A Howe, S Goyal, M Mani – “Inferring the molecular mechanisms that guide developmental bifurcations” (APS)
  • MA Qazi, SK Salim, KR Brown, et al. – “Characterization of the minimal residual disease state reveals distinct evolutionary trajectories of human glioblastoma” (NCBI)

2021

  • SL Freedman, B Xu, S Goyal, M Mani – “A dynamical systems treatment of transcriptomic trajectories in hematopoiesis” (Development)
  • UY Pen, CJ Nunn, S Goyal – “An automated tabletop continuous culturing system with multicolor fluorescence monitoring for microbial gene expression and long-term population dynamics” (ACS Synth. Biol.)
  • M Smart, S Goyal, A Zilman – “Roles of phenotypic heterogeneity and microenvironment feedback in early tumor development” (Phys Rev. E)
  • SK Rehman, J Haynes, E Collignon, et al. – “Colorectal cancer cells enter a diapause-like DTP state to survive chemotherapy” (Cell)
  • SL Freedman, B Xu, S Goyal, M Mani – “Revealing cell-fate bifurcations from transcriptomic trajectories of hematopoiesis”
  • J Rothschild, N Leibovich, A Zilman, S Goyal – “Abundance transitions in multispecies stochastic Lotka-Volterra”
  • S Freedman, B Xu, S Goyal, M Mani – “Detecting bifurcations in tissue development”

2020–2019

  • S Bradde, A Nourmohammad, S Goyal, V Balasubramanian – “The size of the immune repertoire of bacteria”
  • C Nunn, S Goyal – “A model to explain the propagation of small dysfunctional mitochondrial DNAs in budding yeast”
  • S Jatav, S Malhotra, FD Miller, A Jha, S Goyal – “Inferring metabolic rewiring in embryonic neural development using single cell data”
  • N Shakiba, A Fahmy, G Jayakumaran, et al. – “Cell competition during reprogramming gives rise to dominant clones”
  • H Tao, M Zhu, K Lau, OKW Whitley, et al. – “Oscillatory cortical forces promote three dimensional cell intercalations that shape the murine mandibular arch”
  • S Goyal, M Bonsma-Fisher – “How adaptive immunity constrains the composition and fate of large bacterial populations”
  • GC Lui, S Goyal – “What do metabolic constraints inform us about the emergence of early stable bacterial communities?”

2018

  • SG Madeleine Bonsma-Fisher, “How Adaptive Immunity Constrains the Composition and Fate of Large Bacterial Populations”
  • S Dasgupta, GD Bader, “Single-cell RNA Sequencing: A New Window into Cell Scale Dynamics”
  • H Tao, M Zhu, K Lau, “Oscillatory cortical forces promote three dimensional mesenchymal cell intercalations to shape the mandibular arch”
  • N Shakiba, A Fahmy, G Jayakumaran, “Competition During Reprogramming Gives Rise to Deterministically Elite Clones”
  • S McGibbon-Gardner, N Shakiba, P Zandstra, “Competition During Reprogramming Gives Rise to Deterministically Elite Clones”

And before

  • T Chou, S Goyal, S Kim, ISY Chen. “Lineage-tracking of stem cell differentiation: a neutral model of hematopoiesis in rhesus macaque” (2016)
  • S Goyal, S Kim, ISY Chen, T Chou. “Mechanisms of blood homeostasis: lineage tracking and a neutral model of cell populations in rhesus macaques” (2015)
  • S Goyal, PW Zandstra. “Chasing blood” (2015)
  • M Mani, S Goyal, KD Irvine, BI Shraiman. “Collective polarization model for gradient sensing via Dachsous-Fat intercellular signaling” (2013)